Anticandidal activity of certain South Indian medicinal plants.

Vaijayanthimala J, Anandi C, Udhaya V, Pugalendi KV.

Department of Biochemistry, Annamalai University, Annamalainagar - 608 002, Tamil Nadu, India.

The anticandidal activity of 20 household South Indian medicinal plants and/or plant products was studied using 30 Candida albicans isolates obtained from vaginal candidiasis patients of Rajah Muthiah Medical College and Hospital and compared with the anticandidal activity of garlic. Water and ethanol extracts were prepared and their minimum inhibitory concentrations (MIC) and minimum fungicidal concentrations (MFC) were determined. Water extracts of three plants did not show any anticandidal activity, while Murrya koenigii did not exhibit any anticandidal activity in either extract. Other plants exhibited more activity in ethanol extracts showing that their active principle is more soluble in a non-polar solvent.

Phytother Res. 2000 May;14(3):207-9.